Stanislav Gobec, Head of the Department of Pharmaceutical Chemistry, University of Ljubljana Faculty of Pharmacy


alps adria academy conference on dementia :: conference :: keynote speakers :: full prof. stanislav gobec, phd

Full Professor, Head of the Department of Pharmaceutical Chemistry, University of Ljubljana Faculty of Pharmacy

Invited Speaker with the topic:

“Process of basic and pre-clinical research for drug discovery in dementia and related diseases”

1994:

diploma degree, Faculty of Pharmacy, University of Ljubljana.

1999:

doctoral thesis in the field of Medicinal Chemistry.

1994 – 1999:

young Researcher at the Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana.

1999 – 2005:

Assistant Professor.

2005 – 2010:

Associate Professor.

from December 2010:

Full Professor in the Department of Pharmaceutical Chemistry at the University of Ljubljana Faculty of Pharmacy, .

2005-Oct. – 2007:

Vice Dean of the Faculty of Pharmacy.

from. 2007-Oct. – 2011-Oct.:

Dean of the Faculty of Pharmacy, and member of the University of Ljubljana Senate.

from. 2011:

Head of the Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana.

Research interest

(+) Structure-based, in-silico design, synthesis and evaluation of small-molecule enzyme inhibitors. (+) Agents acting on central nervous system. (+) Inhibitors of bacterial cell wall biosynthesis. (+) Antitumour agents. (+) Synthesis of mimetics of natural compounds: peptidomimetics, glycomimetics, lipidomimetics.

Expertise

(+) Drug discovery. (+) Medicinal and pharmaceutical chemistry. (+) In-silico drug design. (+) Virtual high-throughput screening. (+) Organic chemistry. (+) Molecular pharmacology.

VISITING RESEARCHER

University of Leeds

2006

IBBMC, Universite de Paris Sud

2007

Member of editorial and advisory boards

ACS Infectious Diseases

Advisory Board

Acta Chimica Slovenica

Editorial Board

Molecules

Editorial Board

Speaking engagements

Joint Meeting on Medicinal Chemistry

Invited Key-Note Speaker

EFMC International Symposium on Medicinal Chemistry

CONTRIBUTIONS

Author

Author or co-author of more than 200 publications in important peer-reviewed journals.
Two comprehensive book chapters in Houben-Weyl Science of Synthesis.
More than 2.700 pure citations in WoS and 2.900 in SCOPUS.

Patents

Five granted international patents, five international patent applications, seven granted national patents.

Referee

(+) Chemical Reviews, (+) Journal of Medicinal Chemistry, (+) Bioorganic and Medicinal Chemistry, (+) Bioorganic and Medicinal Chemistry Letters, (+) Tetrahedron, (+) Tetrahedron Letters, (+) Archiv der Pharmazie, etc.

Teaching courses

(+) Programme Pharmacy (uniform): Pharmaceutical Chemistry III, Design and Synthesis of Active Substances, Nutritional Supplements. (+) Programme Laboratory Biomedicine (1st stage): Introduction to Biomedical Analysis. (+) Programme Industrial Pharmacy (2nd stage): Pharmaceutical Chemistry, Design of New Active Substances. (‘) Programme Biomedicine (3rd stage): Molecular Basis of Medicinal Chemistry (Module 3, Drugs and Their Targets), Design and synthesis of enzyme inhibitors.

Student supervision

(+) Supervisor/mentor for 86 undergraduate student theses in Pharmacy. (+) Supervisor/mentor for 13 PhD theses.

CURRENT RESEARCH GRANTS

Slovenian Research Agency

(+) Two PhD students (65.000 €/y).
(+) Project leader: Development of multi-functional compounds for treatment of Alzheimer’s disease (200.000 €).

Slovenia-CEA grant with dr. Jacques Philippe-Colletier

Project leader: Parallel optimisation of inhibitors and imaging probes for butyrylcholinesterase, a validated target for Alzheimer’s disease.

Slovenian-Hungarian project (ARRS-NKFIH) with Prof. Dr. György Miklós Keserű

Project partner: Identification of non-peptidic inhibitors of the immunoproteasome using fragment based drug discovery methods.

Membership

European Federation for Medicinal Chemistry (EFMC)

Association Pomurska akademsko znanstvena unija (PAZU), (Eng: Academic Scientific Union of Pomurje region)

Representative publications

(+) Košak et al. J. Med. Chem. 2018, 61: 119-139;
(+) Batson et al. Nat. Commun. 2017, 8: 1393;
(+) Sosič et al. Angew. Chem. 2016, 55: 5745-5748;
(+) Sosič et al. J. Med. Chem. 2015, 58: 9712-9721;
(+) Šink et al. J. Med. Chem. 2015, 58: 613-624.

Full bibliography >>

Let’s meet at the conference.

alps adria conference on dementia :: conference :: keynote speakers :: full prof. stanislav gobec, phd